Ion Chromatography Standards
Apexbio Technology LLC Aliskiren 173334-57-1 1g
Aliskiren (CAS 173334-57-1) is a small-molecule inhibitor that targets human renin an aspartyl protease involved in the regulation of the renin angiotensin aldosterone system (RAAS) By directly inhibiting renin activity Aliskiren suppresses the conversion of angiotensinogen to angiotensin I thereby modulating downstream effects on blood pressure regulation It is clinically approved for the management of essential hypertension In biomedical research Aliskiren serves as a tool compound to investigate RAAS-mediated pathways and the physiological consequences of direct renin inhibition in cardiovascular renal and metabolic disease models
Apexbio Technology LLC Nilotinib monohydrochloride monohydrate 923288-90-8 1g
Nilotinib monohydrochloride monohydrate (CAS 923288-90-8) is a selective small molecule inhibitor targeting the BCR-ABL tyrosine kinase By binding to the ATP-binding site of BCR-ABL nilotinib effectively suppresses kinase activity impeding downstream signaling involved in cell proliferation It demonstrates potent inhibitory activity with an IC50 below 30 nM Nilotinib is widely utilized in biomedical research to investigate BCR-ABL-mediated cellular mechanisms and to model therapeutic interventions in chronic myelogenous leukemia and related malignancies
Inorganic Ventures 1.8 M Methanesulfonic Acid
Inorganic Ventures' 1.8 M Methanesulfonic Acid for ICP-MS is a 100mL reference material set in a water matrix for stability. This eluent is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Inorganic Ventures 1000µg/mL PHTHALATE 125mL
Matrix: Water (H2O), Starting Material: Potassium hydrogen phthalate, Analyte: C6H4(CO2)2-2 1000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Waters Corp IonSABRE Positive Ion Sensitivity Standard
Mass Spectrometry standards kit for system assessment. Ion Sabre positive ion Sensitivity: 1 X 5mg 17-alpha-hydroxyprogesterone 1 X 4 ml Amber Glass with sample prep document Screw Top Vial
Apexbio Technology LLC L-Adrenaline 1g
B1337 is a small molecule designed for biomedical research applications targeting cellular signaling pathways Preliminary studies indicate that B1337 modulates specific protein kinases resulting in altered downstream phosphorylation events Through this mechanism it influences cell proliferation and apoptosis pathways making it a valuable tool for investigating molecular processes underlying cancer and other proliferative disorders B1337 serves as a chemical probe for dissecting kinase-related cellular mechanisms and may facilitate the identification of novel therapeutic targets in oncological and cell biology research
Apexbio Technology LLC Lamotrigine 84057-84-1 1g
Lamotrigine (CAS 84057-84-1) is a small molecule anticonvulsant that acts primarily as a voltage-gated sodium channel blocker stabilizing neuronal membranes and inhibiting repetitive neuronal firing Research indicates that lamotrigine inhibits serotonin (5-HT) uptake with reported IC50 values of 240 M in human platelets and 474 M in rat brain synaptosomes These dual actions on sodium channels and 5-HT transport underline its utility in studies investigating the modulation of excitatory neurotransmission and synaptic function in neurological and psychiatric conditions
Apexbio Technology LLC Triclosan 3380-34-5 1g
Triclosan (CAS 3380-34-5) is a small-molecule inhibitor targeting enoyl-acyl carrier protein reductase (ENR/FabI) a key enzyme involved in bacterial fatty acid synthesis It is designed to inhibit lipid biosynthesis thereby disrupting bacterial growth Triclosan exerts its biological activity primarily through inhibition of FabI In cell-based studies Triclosan demonstrates inhibitory activity with IC50 values of 2 M for Escherichia coli FabI and 10 M for the Gly93 Val FabI mutant It also induces apoptosis in cultured rat neural stem cells Based on these pharmacological properties Triclosan holds research potential in antimicrobial mechanism studies antimicrobial resistance and disease models involving cell apoptosis and inflammation
Apexbio Technology LLC Chondroitin sulfate 9007-28-7 1g
Chondroitin sulfate (9007-28-7) is a glycosaminoglycan designed to modulate inflammatory and apoptotic processes thereby regulating extracellular matrix homeostasis Chondroitin sulfate exerts its biological activity primarily by inhibiting inflammatory mediators and reducing cell apoptosis through interactions with various biological molecules Based on these pharmacological properties chondroitin sulfate holds research potential in investigating cartilage degradation inflammatory response mechanisms and therapeutic targets related to joint degeneration and tissue remodeling
Waters Corp PIC A Low UV Reagent
Paired -Ion Chromatography (PIC Reagents) provide an easy solution for analyzing samples containing ionic species. These reagents allow ionic compounds to be separated by reverse-phase chromatography, saving time by allowing simultaneous assay of acids, bases, amphoteric and neutral compounds. PIC A Low UV is 5 vials/pkg of tertrabutylammonium hydrogen sulfate in a workable UV range in mobile phase 200+ nm.
Apexbio Technology LLC Ofloxacin 82419-36-1 1g
Ofloxacin (CAS 82419-36-1) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV It is designed to inhibit these enzymes thereby blocking bacterial DNA replication and transcription Ofloxacin exerts its biological activity primarily through disruption of DNA supercoiling by binding to the enzyme-DNA complex preventing proper DNA synthesis and bacterial proliferation In in vitro studies ofloxacin demonstrates inhibitory activity with reported IC50 values ranging from 0 5 to 10 g/mL depending on bacterial strain variability and experimental conditions Based on these pharmacological properties ofloxacin holds research potential in microbiological and pharmaceutical studies such as bacterial resistance research evaluation of bacterial enzyme inhibition susceptibility assay validation and investigation of bacterial gene regulation and replication mechanisms
Waters Corp PIC B6 Low UV Reagent
Paired -Ion Chromatography (PIC Reagents) provide an easy solution for analyzing samples containing ionic species. These reagents allow ionic compounds to be separated by reverse-phase chromatography, saving time by allowing simultaneous assay of acids, bases, amphoteric and neutral compounds. PIC B6 Low UV is a 5 vial/pkg of hexane sulfonic acid in a workable UV range in mobile phase 200+ nm.
Inorganic Ventures 1000µg/mL BENZOATE 125mL
Inorganic Ventures' 1000 ppm (µg/mL) Benzoate for IC is a 125mL certified reference material set in a water matrix for stability. This benzoate standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search