Ion Chromatography Standards
Apexbio Technology LLC Aliskiren 173334-57-1 1g
Aliskiren (CAS 173334-57-1) is a small-molecule inhibitor that targets human renin an aspartyl protease involved in the regulation of the renin angiotensin aldosterone system (RAAS) By directly inhibiting renin activity Aliskiren suppresses the conversion of angiotensinogen to angiotensin I thereby modulating downstream effects on blood pressure regulation It is clinically approved for the management of essential hypertension In biomedical research Aliskiren serves as a tool compound to investigate RAAS-mediated pathways and the physiological consequences of direct renin inhibition in cardiovascular renal and metabolic disease models
Apexbio Technology LLC Triclosan 3380-34-5 1g
Triclosan (CAS 3380-34-5) is a small-molecule inhibitor targeting enoyl-acyl carrier protein reductase (ENR/FabI) a key enzyme involved in bacterial fatty acid synthesis It is designed to inhibit lipid biosynthesis thereby disrupting bacterial growth Triclosan exerts its biological activity primarily through inhibition of FabI In cell-based studies Triclosan demonstrates inhibitory activity with IC50 values of 2 M for Escherichia coli FabI and 10 M for the Gly93 Val FabI mutant It also induces apoptosis in cultured rat neural stem cells Based on these pharmacological properties Triclosan holds research potential in antimicrobial mechanism studies antimicrobial resistance and disease models involving cell apoptosis and inflammation
Waters Corp 125 mL Cloride
Chloride Ion Calibration Standard 1000mg/L Martix H2O. This 1000 mg/L standard can be used for primary calibration or to prepare second source calibration check standards. It is traceable to NIST Standard Reference Materials, where available, and is guaranteed stable for one year.
SPEX CERTIPREP LLC 3P NITROGEN 1000UGML NAO2
(HPS by Zeptometrix) Nitrogen (from NaNO2) IC Std 1000 ug/mL in H2O Exp Date: 1 Year
Apexbio Technology LLC Minoxidil 38304-91-5 1g
Minoxidil (CAS 38304-91-5) is a synthetic pyrimidine derivative that functions as a direct-acting vasodilator It exerts its pharmacological effects by opening ATP-sensitive potassium channels in vascular smooth muscle cells leading to membrane hyperpolarization and subsequent relaxation of arterial smooth muscle These actions result in reduced peripheral vascular resistance and lower blood pressure Minoxidil is widely utilized in biomedical research to investigate mechanisms of vasodilation vascular smooth muscle physiology and the role of potassium channels in cardiovascular regulation
Apexbio Technology LLC Candesartan Cilexetil 145040-37-5 1g
Candesartan Cilexetil (CAS 145040-37-5) is a selective angiotensin II receptor antagonist that inhibits the binding of angiotensin II to the AT1 receptor subtype By blocking this interaction it modulates pathways involved in vascular tone and blood pressure regulation In preclinical research Candesartan Cilexetil has been investigated for its capacity to attenuate the progression of pulmonary fibrosis modulate host response in viral infections and facilitate skin wound healing These properties support its utility in studies of cardiovascular pathophysiology fibrotic disease mechanisms viral infection dynamics and tissue repair processes
Apexbio Technology LLC Diuron 330-54-1 1g
Diuron is a small-molecule inhibitor targeting electron transport within chloroplasts It is designed to interfere with photosynthesis by suppressing electron transfer thereby affecting cellular energy metabolism via reduced ATP and NADH synthesis Diuron exerts its biological activity primarily through inhibition of electron transfer in chloroplasts In experimental studies in animal models dietary administration of Diuron at elevated concentrations is associated with increased occurrence of urothelial carcinoma Based on these pharmacological properties Diuron holds research potential in studies of photosynthetic biochemical pathways cellular energy regulation and chemical-induced carcinogenesis
SPEX CERTIPREP LLC 3P CHLORIDE 250 ML 1000PPM
(HPS by Zeptometrix) 1000 ug/mL Chloride in H2O; Single Component IC Standard, 18 Month Expiry Date. Prepared from high-purity salts in 18-megaohm water, packaged in HDPE bottles.
Waters Corp 125 mL Silica
Silica, Ion Calibration Standard 1000mg/L. This 1000 mg/L standard can be used for primary calibration or to prepare second source calibration check standards. It is traceable to NIST Standard Reference Materials, where available, and is guaranteed stable for one year.
Apexbio Technology LLC Clioquinol 130-26-7 1g
Clioquinol (130-26-7) is a small-molecule modulator functioning as a metal-ion chelator It is designed to modulate metal homeostasis thereby affecting metal-dependent cellular pathways Clioquinol exerts its biological activity primarily through chelation of metal ions disrupting iron-mediated enzymatic reactions crucial for fungal and cancer cell growth In in vitro studies Clioquinol demonstrates cytotoxic effects in diverse tumor cell lines with IC50 values generally in the low micromolar range (approximately 1 10 M depending on cell type and conditions) Based on these pharmacological properties Clioquinol holds research potential in antifungal antimicrobial and oncological applications
Apexbio Technology LLC Hematoxylin 517-28-2 1g
Hematoxylin (CAS 517-28-2) is a naturally derived dye obtained from the heartwood of Haematoxylum campechianum Upon oxidation hematoxylin forms a quinone structure that complexes with metal ions such as aluminum or iron producing a cationic dye-metal complex This complex preferentially binds to basophilic cellular components particularly nucleic acids within cell nuclei resulting in prominent nuclear staining Hematoxylin is most commonly applied in combination with eosin in H E staining protocols facilitating differentiation of nuclear and cytoplasmic structures in histological and pathological tissue analysis